DYADIC

Engineering Proteins that Power Progress

About Dyadic

We are a global biotechnology company focused on the large-scale production of high-value, strategic input proteins for non-pharmaceutical applications across the life sciences, food & nutrition, and bioindustrial sectors. These proteins serve as essential components in bioprocessing, formulation, and product development—enabling innovation without the regulatory complexity and high costs associated with therapeutic biologics. While our commercial focus is on non-therapeutic markets, our proprietary platforms retain the capability to produce pharmaceutical biologics, including vaccines and therapeutic proteins, for partners with such needs.

Dyadic’s journey began in the 1980s with industrial enzyme development and advanced significantly in the 1990s with the discovery of its proprietary fungal host, Thermothelomyces heterothallica. Building on this foundation, we have steadily evolved into a leading provider of scalable, precision-engineered protein production solutions. Our platforms have achieved regulatory traction—including GRAS status for food-grade applications, cGMP production capability, and completion of a first-in-human Phase I study—and now enable commercial-scale manufacturing of high-value input proteins for bioprocessing, nutrition, and pharmaceutical applications. This rich foundation gives us strong scalability and technical credibility across both pharma and non-pharma markets.

Our Mission

At Dyadic, our mission is to accelerate access to essential proteins by making biomanufacturing faster, more affordable, and more scalable. From molecular biology reagents to enzymes and animal health inputs, our platforms support a wide range of life science, food, nutrition, and industrial applications. We’re addressing the limitations of conventional bioproduction—where high costs, long development timelines, or scale-up challenges often restrict progress.

Dyadic’s proprietary microbial platforms – C1 and Dapibus™ – leverage the company’s decades of expertise in industrial-scale biomanufacturing and enable rapid, cost-effective development and production of precision-engineered proteins at flexible commercial scales with lower operating costs across expanding biomanufacturing categories.

With over 30 years of innovation, Dyadic is focused on delivering applied biotechnology solutions that support bioprocessing, formulation, and product development across regulated and industrial markets – without the time, expense and regulatory burdens of pharmaceutical biologics. We are actively advancing our internal product pipeline while collaborating with leading global partners to bring next-generation essential proteins in the life science, food and nutrition, and bio industrial markets.

Our Tech

For over two decades, our fungal gene expression platform, Thermothelomyces heterothallica (formerly Myceliophthora thermophila) has been used to produce commercial quantities of industrial enzymes and other proteins. This proprietary and patented technology is a novel genetically engineered thermophilic filamentous fungus that is highly productive and scalable.

Life Sciences

Dyadic’s C1 platform is a robust and versatile gene expression system designed for the efficient production of high-value input proteins that power the life sciences sector – such as cell culture media components, molecular biology reagents, and other critical bioprocessing inputs. While Dyadic is now focused on these non-pharmaceutical applications, the C1 platform retains its demonstrated capabilities for partners developing vaccines, antibodies, and other biopharmaceuticals, supporting a broad range of life sciences innovation from discovery through manufacturing.

Food and Nutrition

Dyadic’s Dapibus™ platform is purpose-built to accelerate the development and scalable production of high-value, non-animal proteins and enzymes for the food and nutrition industry. Engineered for efficiency and flexibility, Dapibus™ enables the cost-effective manufacture of key ingredients such as alpha-lactalbumin and other non-animal dairy proteins, as well as enzymes and functional proteins used in a range of food and wellness products. The platform is designed to support sustainable, animal-free innovation to meet the growing global demand for advanced nutritional solutions.

Bio Industrial

Dyadic’s Dapibus™ platform is designed to deliver sustainable, cost-effective enzyme and protein solutions for large-scale bioindustrial applications. Through internal development and strategic partnerships, Dyadic is leveraging Dapibus™ to produce high-performance enzymes for biomass processing and biofuels, among other industrial uses. The platform’s scalability and efficiency position it to meet the growing demand for environmentally responsible, economically viable bioindustrial inputs that support the transition to a more sustainable bioeconomy.

Our Solutions

Microbial Platforms

Dyadic is building next-generation microbial platforms to meet the growing global demand for high-value, non-animal proteins and enzymes. Our proprietary expression systems are engineered to deliver scalable, cost-effective solutions powering innovation in life science research and bioprocessing, food and nutrition, and sustainable bioindustrial processes. By focusing on essential input proteins, we are helping our partners bring advanced, animal-free products to market faster and more affordably.

Protein Products

Dyadic is developing a growing portfolio of high-value input proteins for non-pharmaceutical applications across life sciences, food and nutrition, and industrial biotechnology. Our current pipeline includes recombinant proteins for use in cell culture media, diagnostics, molecular biology reagents, and functional food ingredients – such as recombinant human serum albumin, non-animal dairy products and biomass processing enzymes. In parallel, Dyadic’s platforms remain available to partners interested in leveraging our technology for the development of vaccines, antibodies, and other biologics.